FREQUENTLY ASKED QUESTIONS?

Who is PrEP for?

PrEP is for anyone who wants some extra protection against HIV. Your doctor or healthcare provide can help you decide if PrEP is a good fit for you. If you or your partner use injection drugs, PrEP may also help protect against HIV. You can find access to PrEP online as well.

How much does PrEP cost?

PrEP is available for free through most insurance providers, including Medicaid and Medicare. If you are uninsured, there are patient assistance programs available to help cover all expenses related to PrEP.

Services like MISTR help get your completely free PrEP in all 50 states including DC and Puerto Rico.

Does Medicaid cover PrEP? Medicare?

Yes. Both Medicaid, as well as Medicare, will cover PrEP.

Who can take PrEP?

There is a PrEP option for everyone.

Truvada for PrEP can be taken by any adults or adolescents over 77 pounds who are HIV negative.

Descovy for PrEP is only available to those assigned male at birth who weigh at least 77 pounds.

How long does it take for PrEP to become effective?

PrEP takes about 7 days before it is fully effective in rectal tissue, and take up to 20 days for vaginal tissue. However, the CDC recommends taking PrEP every day for 21 days prior to any possible exposure to HIV. The drug must be potent enough in the bloodstream to block HIV infection. Taking a pill right before or immediately after possible exposure to the virus will not protect against a potential HIV infection.

Can I take PrEP sporadically?

PrEP is most effective when taken every single day. If you take PrEP daily, the level of protection is about 99%. If you take PrEP four times per week, the level of protection is about 96%. When taken less than 4 days per week, the potency of the drug in the bloodstream is greatly reduced, and the drug’s effectiveness drops dramatically. If you miss a dose, make sure to take the next one, but there is no need to double up.

What are the side effects of PrEP

Those taking PrEP report little to no side effects, but symptoms such as headache, abdominal pain, and weight loss can happen. These side effects typically do not last long and often go away entirely within the first month. If you’re experiencing prolonged side effects, please let your doctor know.

Is it safe to take PrEP while on other medications?


Yes, but you should always disclose what other medications you’re on to your prescribing physician. 

Still have more questions?

If you need more information about free online PrEP and resources available to you, you should visit MISTR and receive answers to all your questions.

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